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Active Microneedle Administration of Plant Virus Nanoparticles for Cancer in situ Vaccination Improves Immunotherapeutic Efficacy

The solid tumor microenvironment (TME) poses a significant structural and biochemical barrier to immunotherapeutic agents. To address the limitations of tumor penetration and distribution, and to enhance antitumor efficacy of immunotherapeutics, we present here an autonomous active microneedle (MN)...

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Bibliografiske detaljer
Udgivet i:ACS Appl Nano Mater
Main Authors: Boone, Christine E., Wang, Chao, Lopez-Ramirez, Miguel Angel, Beiss, Veronique, Shukla, Sourabh, Chariou, Paul L., Kupor, Daniel, Rueda, Ricardo, Wang, Joseph, Steinmetz, Nicole F.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101548/
https://ncbi.nlm.nih.gov/pubmed/33969278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsanm.0c01506
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