Complex Landscape of Alternative Splicing in Myeloid Neoplasms

Myeloid neoplasms are characterized by frequent mutations in at least seven components of the spliceosome that have distinct roles in the process of pre-mRNA splicing. Hotspot mutations in SF3B1, SRSF2, U2AF1 and loss of function mutations in ZRSR2 have revealed widely different aberrant splicing si...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Hershberger, Courtney E., Moyer, Devlin C., Adema, Vera, Kerr, Cassandra M., Walter, Wencke, Hutter, Stephan, Meggendorfer, Manja, Baer, Constance, Kern, Wolfgang, Nadarajah, Niroshan, Twardziok, Sven, Sekeres, Mikkael A., Haferlach, Claudia, Haferlach, Torsten, Maciejewski, Jaroslaw P., Padgett, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101081/
https://ncbi.nlm.nih.gov/pubmed/32753690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-1002-y
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