Complex Landscape of Alternative Splicing in Myeloid Neoplasms

Myeloid neoplasms are characterized by frequent mutations in at least seven components of the spliceosome that have distinct roles in the process of pre-mRNA splicing. Hotspot mutations in SF3B1, SRSF2, U2AF1 and loss of function mutations in ZRSR2 have revealed widely different aberrant splicing si...

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Detaylı Bibliyografya
Yayımlandı:Leukemia
Asıl Yazarlar: Hershberger, Courtney E., Moyer, Devlin C., Adema, Vera, Kerr, Cassandra M., Walter, Wencke, Hutter, Stephan, Meggendorfer, Manja, Baer, Constance, Kern, Wolfgang, Nadarajah, Niroshan, Twardziok, Sven, Sekeres, Mikkael A., Haferlach, Claudia, Haferlach, Torsten, Maciejewski, Jaroslaw P., Padgett, Richard A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101081/
https://ncbi.nlm.nih.gov/pubmed/32753690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-1002-y
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