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Investigations into the synthesis of a nucleotide dimer via mechanochemical phosphoramidite chemistry
Liquid-assisted mechanochemistry as a versatile approach for the coupling of a nucleoside phosphoramidite with a 5′-OH partially protected nucleoside has been investigated. Noted advantages over reported methods were a simplified reaction protocol, a drastic reduction in the use of toxic solvents, t...
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| Publicado no: | R Soc Open Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8101013/ https://ncbi.nlm.nih.gov/pubmed/34035937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.201703 |
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