Cryptotanshinone Inhibits ERα-Dependent and -Independent BCRP Oligomer Formation to Reverse Multidrug Resistance in Breast Cancer

Both long-term anti-estrogen therapy and estrogen receptor-negative breast cancer contribute to drug resistance, causing poor prognosis in breast cancer patients. Breast cancer resistance protein (BCRP) plays an important role in multidrug resistance. Here, we show that cryptotanshinone (CPT), an an...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Ni, Wenting, Fan, Hui, Zheng, Xiuqin, Xu, Fangming, Wu, Yuanyuan, Li, Xiaoman, Wang, Aiyun, Huang, Shile, Chen, Wenxing, Wang, Shijun, Lu, Yin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100513/
https://ncbi.nlm.nih.gov/pubmed/33968724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.624811
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