Cryptotanshinone inhibition of mammalian target of rapamycin pathway is dependent on oestrogen receptor alpha in breast cancer

Cryptotanshinone (CPT) has been demonstrated to inhibit proliferation and mammalian target of rapamycin (mTOR) pathway in MCF‐7 breast cancer cells. However, the same results are unable to be repeated in MDA‐MB‐231 cells. Given the main difference of oestrogen receptor α (ERα) between two types of b...

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Publicat a:J Cell Mol Med
Autors principals: Pan, Yanhong, Shi, Junfeng, Ni, Wenting, Liu, Yuping, Wang, Siliang, Wang, Xu, Wei, Zhonghong, Wang, Aiyun, Chen, Wenxing, Lu, Yin
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571522/
https://ncbi.nlm.nih.gov/pubmed/28272775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13135
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