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Cryptotanshinone inhibition of mammalian target of rapamycin pathway is dependent on oestrogen receptor alpha in breast cancer

Cryptotanshinone (CPT) has been demonstrated to inhibit proliferation and mammalian target of rapamycin (mTOR) pathway in MCF‐7 breast cancer cells. However, the same results are unable to be repeated in MDA‐MB‐231 cells. Given the main difference of oestrogen receptor α (ERα) between two types of b...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Pan, Yanhong, Shi, Junfeng, Ni, Wenting, Liu, Yuping, Wang, Siliang, Wang, Xu, Wei, Zhonghong, Wang, Aiyun, Chen, Wenxing, Lu, Yin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571522/
https://ncbi.nlm.nih.gov/pubmed/28272775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13135
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