Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer

BACKGROUND: The Glycine N-acyltransferase (GLYAT) gene encodes a protein that catalyzes the transfer of acyl groups from acyl CoA to glycine, resulting in acyl glycine and coenzyme A. Aberrant GLYAT expression is associated with several malignant tumors, but its clinical importance in human breast c...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Tian, Xin, Wu, Lina, Jiang, Min, Zhang, Zhenyong, Wu, Rong, Miao, Jianing, Liu, Caigang, Gao, Song
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100313/
https://ncbi.nlm.nih.gov/pubmed/33968740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.641399
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