Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer

BACKGROUND: The Glycine N-acyltransferase (GLYAT) gene encodes a protein that catalyzes the transfer of acyl groups from acyl CoA to glycine, resulting in acyl glycine and coenzyme A. Aberrant GLYAT expression is associated with several malignant tumors, but its clinical importance in human breast c...

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Publicat a:Front Oncol
Autors principals: Tian, Xin, Wu, Lina, Jiang, Min, Zhang, Zhenyong, Wu, Rong, Miao, Jianing, Liu, Caigang, Gao, Song
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100313/
https://ncbi.nlm.nih.gov/pubmed/33968740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.641399
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