Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation

Osteoporosis and other manifestations of bone disease are frequent in patients with systemic mastocytosis (SM) in association with the presence of mast cell infiltrates in bone marrow, although the mechanisms behind bone disease remain poorly understood. We find that extracellular vesicles (EVs) rel...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Kim, Do-Kyun, Bandara, Geethani, Cho, Young-Eun, Komarow, Hirsh D., Donahue, Danielle R., Karim, Baktiar, Baek, Moon-Chang, Kim, Ho Min, Metcalfe, Dean D., Olivera, Ana
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100305/
https://ncbi.nlm.nih.gov/pubmed/33953168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22754-4
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