Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis

Neoplastic accumulation of mast cells in systemic mastocytosis (SM) associates with activating mutations in the receptor tyrosine kinase KIT. Constitutive activation of tyrosine kinase oncogenes has been linked to imbalances in oxidant/antioxidant mechanisms in other myeloproliferative disorders. Ho...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Do-Kyun, Beaven, Michael A., Kulinski, Joseph M., Desai, Avanti, Bandara, Geethani, Bai, Yun, Prussin, Calman, Schwartz, Lawrence B., Komarow, Hirsh, Metcalfe, Dean D., Olivera, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017616/
https://ncbi.nlm.nih.gov/pubmed/27611333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162831
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