Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis

Neoplastic accumulation of mast cells in systemic mastocytosis (SM) associates with activating mutations in the receptor tyrosine kinase KIT. Constitutive activation of tyrosine kinase oncogenes has been linked to imbalances in oxidant/antioxidant mechanisms in other myeloproliferative disorders. Ho...

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Veröffentlicht in:PLoS One
Hauptverfasser: Kim, Do-Kyun, Beaven, Michael A., Kulinski, Joseph M., Desai, Avanti, Bandara, Geethani, Bai, Yun, Prussin, Calman, Schwartz, Lawrence B., Komarow, Hirsh, Metcalfe, Dean D., Olivera, Ana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017616/
https://ncbi.nlm.nih.gov/pubmed/27611333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162831
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