Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis

Neoplastic accumulation of mast cells in systemic mastocytosis (SM) associates with activating mutations in the receptor tyrosine kinase KIT. Constitutive activation of tyrosine kinase oncogenes has been linked to imbalances in oxidant/antioxidant mechanisms in other myeloproliferative disorders. Ho...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Kim, Do-Kyun, Beaven, Michael A., Kulinski, Joseph M., Desai, Avanti, Bandara, Geethani, Bai, Yun, Prussin, Calman, Schwartz, Lawrence B., Komarow, Hirsh, Metcalfe, Dean D., Olivera, Ana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017616/
https://ncbi.nlm.nih.gov/pubmed/27611333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162831
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