Stochastic Episodes of Latent Cytomegalovirus Transcription Drive CD8 T-Cell “Memory Inflation” and Avoid Immune Evasion

Acute infection with murine cytomegalovirus (mCMV) is controlled by CD8(+) T cells and develops into a state of latent infection, referred to as latency, which is defined by lifelong maintenance of viral genomes but absence of infectious virus in latently infected cell types. Latency is associated w...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Griessl, Marion, Renzaho, Angelique, Freitag, Kirsten, Seckert, Christof K., Reddehase, Matthias J., Lemmermann, Niels A. W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100209/
https://ncbi.nlm.nih.gov/pubmed/33968074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.668885
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