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Stochastic Episodes of Latent Cytomegalovirus Transcription Drive CD8 T-Cell “Memory Inflation” and Avoid Immune Evasion

Acute infection with murine cytomegalovirus (mCMV) is controlled by CD8(+) T cells and develops into a state of latent infection, referred to as latency, which is defined by lifelong maintenance of viral genomes but absence of infectious virus in latently infected cell types. Latency is associated w...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Griessl, Marion, Renzaho, Angelique, Freitag, Kirsten, Seckert, Christof K., Reddehase, Matthias J., Lemmermann, Niels A. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100209/
https://ncbi.nlm.nih.gov/pubmed/33968074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.668885
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