The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis

In the past decade, many long noncoding RNAs (lncRNAs) have been identified and their in vitro functions defined, although in some cases their functions in vivo remain less clear. Moreover, unlike nuclear lncRNAs, the roles of cytoplasmic lncRNAs are less defined. Here, using a gene trapping approac...

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Publicado no:Nat Commun
Main Authors: Sato, Michio, Kadomatsu, Tsuyoshi, Miyata, Keishi, Warren, Junco S., Tian, Zhe, Zhu, Shunshun, Horiguchi, Haruki, Makaju, Aman, Bakhtina, Anna, Morinaga, Jun, Sugizaki, Taichi, Hirashima, Kaname, Yoshinobu, Kumiko, Imasaka, Mai, Araki, Masatake, Komohara, Yoshihiro, Wakayama, Tomohiko, Nakagawa, Shinichi, Franklin, Sarah, Node, Koichi, Araki, Kimi, Oike, Yuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099897/
https://ncbi.nlm.nih.gov/pubmed/33953175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22735-7
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