Treatment of diabetic mice with the SGLT2 inhibitor TA-1887 antagonizes diabetic cachexia and decreases mortality

A favorable effect of an inhibitor of the sodium–glucose cotransporter 2 (SGLT2i) on mortality of diabetic patients was recently reported, although mechanisms underlying that effect remained unclear. Here, we examine SGLT2i effects on survival of diabetic mice and assess factors underlying these out...

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Detalhes bibliográficos
Publicado no:NPJ Aging Mech Dis
Main Authors: Sugizaki, Taichi, Zhu, Shunshun, Guo, Ge, Matsumoto, Akiko, Zhao, Jiabin, Endo, Motoyoshi, Horiguchi, Haruki, Morinaga, Jun, Tian, Zhe, Kadomatsu, Tsuyoshi, Miyata, Keishi, Itoh, Hiroshi, Oike, Yuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591191/
https://ncbi.nlm.nih.gov/pubmed/28900540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41514-017-0012-0
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