Survival of detached cancer cells is regulated by movement of intracellular Na(+),K(+)-ATPase

Beginning of metastasis, cancer cells detach from the primary tumor and they can survive even under loss of anchorage; however, the detachment-elicited mechanisms have remained unknown. Here, we found that Na(+),K(+)-ATPase α3-isoform (α3NaK) in human cancer cells is dynamically translocated from in...

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Veröffentlicht in:iScience
Hauptverfasser: Fujii, Takuto, Shimizu, Takahiro, Katoh, Mizuki, Nagamori, Shushi, Koizumi, Keiichi, Fukuoka, Junya, Tabuchi, Yoshiaki, Sawaguchi, Akira, Okumura, Tomoyuki, Shibuya, Kazuto, Fujii, Tsutomu, Takeshima, Hiroshi, Sakai, Hideki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099779/
https://ncbi.nlm.nih.gov/pubmed/33997694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102412
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