Identification of novel targets of miR-622 in hepatocellular carcinoma reveals common regulation of cooperating genes and outlines the oncogenic role of zinc finger CCHC-type containing 11

The poor prognosis of advanced hepatocellular carcinoma (HCC) is driven by diverse features including dysregulated microRNAs inducing drug resistance and stemness. Lin-28 homolog A (LIN28A) and its partner zinc finger CCHC-type containing 11 (ZCCHC11) cooperate in binding, oligouridylation and subse...

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Veröffentlicht in:Neoplasia
Hauptverfasser: Gaza, Anne, Fritz, Valerie, Malek, Lara, Wormser, Laura, Treiber, Nora, Danner, Johannes, Kremer, Andreas E., Thasler, Wolfgang E., Siebler, Jürgen, Meister, Gunter, Neurath, Markus F., Hellerbrand, Claus, Bosserhoff, Anja K., Dietrich, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press 2021
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099721/
https://ncbi.nlm.nih.gov/pubmed/33901943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2021.04.001
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