Combined De-Repression of Chemoresistance Associated Mitogen-Activated Protein Kinase 14 and Activating Transcription Factor 2 by Loss of microRNA-622 in Hepatocellular Carcinoma

SIMPLE SUMMARY: Novel approaches to target RAS-signaling have led to the so called “RAS renaissance”. In HCC, it was demonstrated that wild-type RAS-RAF-ERK-signaling strongly contributes to HCC progression and drug resistance. In this context, microRNA-622 has emerged as one of the most promising t...

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Publicat a:Cancers (Basel)
Autors principals: Fritz, Valerie, Malek, Lara, Gaza, Anne, Wormser, Laura, Appel, Majken, Kremer, Andreas E., Thasler, Wolfgang E., Siebler, Jürgen, Neurath, Markus F., Hellerbrand, Claus, Bosserhoff, Anja K., Dietrich, Peter
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967205/
https://ncbi.nlm.nih.gov/pubmed/33803354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13051183
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