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The Mediator complex kinase module is necessary for fructose regulation of liver glycogen levels through induction of glucose-6-phosphatase catalytic subunit (G6pc)

OBJECTIVE: Liver glycogen levels are dynamic and highly regulated by nutrient availability as the levels decrease during fasting and are restored during the feeding cycle. However, feeding in the presence of fructose in water suppresses glycogen accumulation in the liver by upregulating the expressi...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Youn, Dou Yeon, Xiaoli, Alus M., Zong, Haihong, Okada, Junichi, Liu, Li, Pessin, Jacob, Pessin, Jeffrey E., Yang, Fajun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099662/
https://ncbi.nlm.nih.gov/pubmed/33812059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101227
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