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Detecting placebo and drug effects on Parkinson's disease symptoms by longitudinal item‐score models
This study tested the hypothesis that analyzing longitudinal item scores of the Unified Parkinson's Disease Rating Scale could allow a smaller trial size and describe a drug's effect on symptom progression. Two historical studies of the dopaminergic drug ropinirole were analyzed: a cross‐o...
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| Publicado en: | CPT Pharmacometrics Syst Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8099436/ https://ncbi.nlm.nih.gov/pubmed/33951753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12601 |
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