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Item Response Theory to Quantify Longitudinal Placebo and Paliperidone Effects on PANSS Scores in Schizophrenia
As biomarkers are lacking, multi‐item questionnaire‐based tools like the Positive and Negative Syndrome Scale (PANSS) are used to quantify disease severity in schizophrenia. Analyzing composite PANSS scores as continuous data discards information and violates the numerical nature of the scale. Here...
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Publicado no: | CPT Pharmacometrics Syst Pharmacol |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5572362/ https://ncbi.nlm.nih.gov/pubmed/28571119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12207 |
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