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The LRR-TM protein PAN-1 interacts with MYRF to promote its nuclear translocation in synaptic remodeling

Neural circuits develop through a plastic phase orchestrated by genetic programs and environmental signals. We have identified a leucine-rich-repeat domain transmembrane protein PAN-1 as a factor required for synaptic rewiring in C. elegans. PAN-1 localizes on cell membrane and binds with MYRF, a me...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Xia, Shi-Li, Li, Meng, Chen, Bing, Wang, Chao, Yan, Yong-Hong, Dong, Meng-Qiu, Qi, Yingchuan B
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099431/
https://ncbi.nlm.nih.gov/pubmed/33950834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.67628
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