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Recent Advances in Elucidating Niemann‐Pick C Disease
Lysosomal sequestration of endocytosed LDL‐derived cholesterol, premature and abnormal enrichment of cholesterol in trans Golgi cisternae and accompanying anomalies in intracellular sterol trafficking are the hallmark phenotypic features of the Niemann‐Pick C (NPC) lesion. A variable severity of the...
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| Publicado no: | Brain Pathol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8098395/ https://ncbi.nlm.nih.gov/pubmed/9458174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.1998.tb00143.x |
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