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Apolipoprotein E Isoforms Increase Intracellular Ca(2+) Differentially Through a ω‐Agatoxin IVa‐Sensitive Ca(2+)‐Channel
Apolipoprotein E (apoE) is the major apolipoprotein in the brain and is known for its important role in plasticity and neurodegeneration. We show that apoE dose‐dependently increases intracellular free Ca(2+) in rat hippocampal astrocytes and neurons. This effect varies with isoforms in the order E4...
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| Publicado no: | Brain Pathol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8098222/ https://ncbi.nlm.nih.gov/pubmed/9804373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.1998.tb00190.x |
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