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Preferential Interaction of ω-Conotoxins with Inactivated N-type Ca(2+) Channels

The selective block of N-type Ca(2+) channels by ω-conotoxins has been a hallmark of these channels, critical in delineating their biological roles and molecular characteristics. Here we report that the ω-conotoxin-channel interaction depends strongly on channel gating. N-type channels (α(1B), α(2),...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Stocker, Jonathan W., Nadasdi, Laszlo, Aldrich, Richard W., Tsien, Richard W.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573648/
https://ncbi.nlm.nih.gov/pubmed/9096136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-09-03002.1997
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