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Analgesic effect of highly reversible ω-conotoxin FVIA on N type Ca(2+ )channels
BACKGROUND: N-type Ca(2+ )channels (Ca(v)2.2) play an important role in the transmission of pain signals to the central nervous system. ω-Conotoxin (CTx)-MVIIA, also called ziconotide (Prialt(®)), effectively alleviates pain, without causing addiction, by blocking the pores of these channels. Unfort...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025903/ https://ncbi.nlm.nih.gov/pubmed/21172037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-97 |
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