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Creutzfeldt‐Jakob Disease: Carnoy's Fixative Improves the Immunohistochemistry of the Proteinase K‐ Resistant Prion Protein

The neuropathological diagnosis of Creutzfeldt‐Jakob disease relies on the immunohistochemical demonstration of the proteinase‐K resistant form of the prion protein (PrP(res)) in the brain tissue. The antigenicity of PrP(res) is strongly reduced by the formalin solution widely used to fix the tissue...

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Bibliografiska uppgifter
I publikationen:Brain Pathol
Huvudupphovsmän: Giaccone, Giorgio, Canciani, Barbara, Puoti, Gianfranco, Rossi, Giacomina, Goffredo, Donato, Iussich, Selina, Fociani, Paolo, Tagliavini, Fabrizio, Bugiani, Orso
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098189/
https://ncbi.nlm.nih.gov/pubmed/10668893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2000.tb00240.x
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