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A novel estimator of the interaction matrix in Graphical Gaussian Model of omics data using the entropy of non-equilibrium systems

MOTIVATION: Inferring the direct relationships between biomolecules from omics datasets is essential for the understanding of biological and disease mechanisms. Gaussian Graphical Model (GGM) provides a fairly simple and accurate representation of these interactions. However, estimation of the assoc...

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Vydáno v:Bioinformatics
Hlavní autoři: Borzou, Ahmad, Sadygov, Rovshan G
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098027/
https://ncbi.nlm.nih.gov/pubmed/33067612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa894
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