Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson’s disease brain

BACKGROUND: Parkinson’s disease (PD) is a complex, age-related neurodegenerative disorder of largely unknown etiology. PD is strongly associated with mitochondrial respiratory dysfunction, which can lead to epigenetic dysregulation and specifically altered histone acetylation. Nevertheless, and desp...

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發表在:Mol Neurodegener
Main Authors: Toker, Lilah, Tran, Gia T., Sundaresan, Janani, Tysnes, Ole-Bjørn, Alves, Guido, Haugarvoll, Kristoffer, Nido, Gonzalo S., Dölle, Christian, Tzoulis, Charalampos
格式: Artigo
語言:Inglês
出版: BioMed Central 2021
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097820/
https://ncbi.nlm.nih.gov/pubmed/33947435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-021-00450-7
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