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Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci

Parkinson disease (PD) is a complex neurodegenerative disorder influenced by both environmental and genetic factors. While genome wide association studies have identified several susceptibility loci, many causal variants and genes underlying these associations remain undetermined. Identifying these...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gaare, Johannes Jernqvist, Nido, Gonzalo, Dölle, Christian, Sztromwasser, Paweł, Alves, Guido, Tysnes, Ole-Bjørn, Haugarvoll, Kristoffer, Tzoulis, Charalampos
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529297/
https://ncbi.nlm.nih.gov/pubmed/33002040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239824
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