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Finding long tandem repeats in long noisy reads

MOTIVATION: Long tandem repeat expansions of more than 1000 nt have been suggested to be associated with diseases, but remain largely unexplored in individual human genomes because read lengths have been too short. However, new long-read sequencing technologies can produce single reads of 10 000 nt...

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Dettagli Bibliografici
Pubblicato in:Bioinformatics
Autori principali: Morishita, Shinichi, Ichikawa, Kazuki, Myers, Eugene W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097686/
https://ncbi.nlm.nih.gov/pubmed/33031558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa865
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