Effect of Therapeutic Drug Monitoring vs Standard Therapy During Infliximab Induction on Disease Remission in Patients With Chronic Immune-Mediated Inflammatory Diseases: A Randomized Clinical Trial

IMPORTANCE: Proactive therapeutic drug monitoring (TDM), defined as individualized drug dosing based on scheduled monitoring of serum drug levels, has been proposed as an alternative to standard therapy to maximize efficacy and safety of infliximab and other biological drugs. However, whether proact...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Syversen, Silje Watterdal, Goll, Guro Løvik, Jørgensen, Kristin Kaasen, Sandanger, Øystein, Sexton, Joseph, Olsen, Inge Christoffer, Gehin, Johanna Elin, Warren, David John, Brun, Marthe Kirkesæther, Klaasen, Rolf Anton, Karlsen, Lars Normann, Noraberg, Geir, Zettel, Camilla, Ljoså, Maud Kristine Aga, Haugen, Anne Julsrud, Njålla, Rune Johan, Bruun, Trude Jannecke, Seeberg, Kathrine Aglen, Michelsen, Brigitte, Strand, Eldri Kveine, Skorpe, Svanaug, Blomgren, Ingrid Marianne, Bragnes, Yngvill Hovde, Dotterud, Christian Kvikne, Thune, Turid, Ystrøm, Carl Magnus, Torp, Roald, Mielnik, Pawel, Mørk, Cato, Kvien, Tore K., Jahnsen, Jørgen, Bolstad, Nils, Haavardsholm, Espen A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2021
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097498/
https://ncbi.nlm.nih.gov/pubmed/33944876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2021.4172
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