Heterologous Expression of ethA and katG in Mycobacterium marinum Enables the Rapid Identification of New Prodrugs Active against Mycobacterium tuberculosis

Screening strategies for antituberculosis compounds using Mycobacterium tuberculosis are time consuming and require biosafety level 3 (BSL3) facilities, which makes the development of high-throughput assays difficult and expensive. Mycobacterium marinum, a close genetic relative of M. tuberculosis,...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Ho, Vien Q. T., Verboom, Theo, Rong, Mark K., Habjan, Eva, Bitter, Wilbert, Speer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2021
Assuntos:
Susceptibility
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097478/
https://ncbi.nlm.nih.gov/pubmed/33495223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01445-20
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