Synergistic Quinolone Sensitization by Targeting the recA SOS Response Gene and Oxidative Stress

Suppression of the recA SOS response gene and reactive oxygen species (ROS) overproduction have been shown, separately, to enhance fluoroquinolone activity and lethality. Their putative synergistic impact as a strategy to potentiate the efficacy of bactericidal antimicrobial agents such as fluoroqui...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Diaz-Diaz, S., Recacha, E., Machuca, J., García-Duque, A., Docobo-Pérez, F., Blázquez, J., Pascual, A., Rodríguez-Martínez, J. M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2021
Gaiak:
Mechanisms of Action: Physiological Effects
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097469/
https://ncbi.nlm.nih.gov/pubmed/33526493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02004-20
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