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Synergistic Quinolone Sensitization by Targeting the recA SOS Response Gene and Oxidative Stress

Suppression of the recA SOS response gene and reactive oxygen species (ROS) overproduction have been shown, separately, to enhance fluoroquinolone activity and lethality. Their putative synergistic impact as a strategy to potentiate the efficacy of bactericidal antimicrobial agents such as fluoroqui...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Diaz-Diaz, S., Recacha, E., Machuca, J., García-Duque, A., Docobo-Pérez, F., Blázquez, J., Pascual, A., Rodríguez-Martínez, J. M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097469/
https://ncbi.nlm.nih.gov/pubmed/33526493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02004-20
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