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Metabolic Survival Adaptations of Plasmodium falciparum Exposed to Sublethal Doses of Fosmidomycin

The malaria parasite Plasmodium falciparum contains the apicoplast organelle that synthesizes isoprenoids, which are metabolites necessary for posttranslational modification of Plasmodium proteins. We used fosmidomycin, an antibiotic that inhibits isoprenoid biosynthesis, to identify mechanisms that...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Tewari, Shivendra G., Rajaram, Krithika, Swift, Russell P., Reifman, Jaques, Prigge, Sean T., Wallqvist, Anders
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097461/
https://ncbi.nlm.nih.gov/pubmed/33495219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02392-20
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