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Variability of Hydroxy-Itraconazole in Relation to Itraconazole Bloodstream Concentrations
We analyzed the relationship between itraconazole (ITZ) and hydroxy-itraconazole (OH-ITZ) levels in 1,223 human samples. Overall, there was a statistically significant correlation between ITZ and OH-ITZ levels (Pearson’s r, 0.7838), and OH-ITZ levels were generally higher than ITZ levels (median OH-...
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| Publicado no: | Antimicrob Agents Chemother |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8097436/ https://ncbi.nlm.nih.gov/pubmed/33468480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02353-20 |
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