Activity of Cefepime in Combination with the Novel β-Lactamase Inhibitor Taniborbactam (VNRX-5133) against Extended-Spectrum-β-Lactamase-Producing Isolates in In Vitro Checkerboard Assays

Extended-spectrum-β-lactamase (ESBL)-producing strains are increasing worldwide, limiting therapeutic options. Taniborbactam (VNRX-5133) is a newly developed β-lactamase inhibitor with a wide spectrum of activity covering both serine and metallo enzymes. We therefore evaluated cefepime-taniborbactam...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Kloezen, Wendy, Melchers, Ria J., Georgiou, Panagiota-Christina, Mouton, Johan W., Meletiadis, Joseph
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2021
Matèries:
Susceptibility
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097409/
https://ncbi.nlm.nih.gov/pubmed/33431413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02338-20
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