Hsp90‐mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling

Stress granules (SGs) are dynamic condensates associated with protein misfolding diseases. They sequester stalled mRNAs and signaling factors, such as the mTORC1 subunit raptor, suggesting that SGs coordinate cell growth during and after stress. However, the molecular mechanisms linking SG dynamics...

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Bibliografske podrobnosti
izdano v:EMBO Rep
Main Authors: Mediani, Laura, Antoniani, Francesco, Galli, Veronica, Vinet, Jonathan, Carrà, Arianna Dorotea, Bigi, Ilaria, Tripathy, Vadreenath, Tiago, Tatiana, Cimino, Marco, Leo, Giuseppina, Amen, Triana, Kaganovich, Daniel, Cereda, Cristina, Pansarasa, Orietta, Mandrioli, Jessica, Tripathi, Priyanka, Troost, Dirk, Aronica, Eleonora, Buchner, Johannes, Goswami, Anand, Sterneckert, Jared, Alberti, Simon, Carra, Serena
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2021
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097338/
https://ncbi.nlm.nih.gov/pubmed/33738926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051740
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