Hsp90‐mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling

Stress granules (SGs) are dynamic condensates associated with protein misfolding diseases. They sequester stalled mRNAs and signaling factors, such as the mTORC1 subunit raptor, suggesting that SGs coordinate cell growth during and after stress. However, the molecular mechanisms linking SG dynamics...

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Opis bibliograficzny
Wydane w:EMBO Rep
Główni autorzy: Mediani, Laura, Antoniani, Francesco, Galli, Veronica, Vinet, Jonathan, Carrà, Arianna Dorotea, Bigi, Ilaria, Tripathy, Vadreenath, Tiago, Tatiana, Cimino, Marco, Leo, Giuseppina, Amen, Triana, Kaganovich, Daniel, Cereda, Cristina, Pansarasa, Orietta, Mandrioli, Jessica, Tripathi, Priyanka, Troost, Dirk, Aronica, Eleonora, Buchner, Johannes, Goswami, Anand, Sterneckert, Jared, Alberti, Simon, Carra, Serena
Format: Artigo
Język:Inglês
Wydane: John Wiley and Sons Inc. 2021
Hasła przedmiotowe:
Articles
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097338/
https://ncbi.nlm.nih.gov/pubmed/33738926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051740
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