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Fast and Robust Identity-by-Descent Inference with the Templated Positional Burrows–Wheeler Transform

Estimating the genomic location and length of identical-by-descent (IBD) segments among individuals is a crucial step in many genetic analyses. However, the exponential growth in the size of biobank and direct-to-consumer genetic data sets makes accurate IBD inference a significant computational cha...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Biol Evol
Main Authors: Freyman, William A, McManus, Kimberly F, Shringarpure, Suyash S, Jewett, Ethan M, Bryc, Katarzyna, Auton, Adam
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097300/
https://ncbi.nlm.nih.gov/pubmed/33355662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msaa328
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