Inference of identity by descent in population isolates and optimal sequencing studies

In an isolated population, individuals are likely to share large genetic regions inherited from common ancestors. Identity by descent (IBD) can be inferred from SNP genotypes, which is useful in a number of applications, including identifying genetic variants influencing complex disease risk, and pl...

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Detalhes bibliográficos
Main Authors: Glodzik, Dominik, Navarro, Pau, Vitart, Veronique, Hayward, Caroline, McQuillan, Ruth, Wild, Sarah H, Dunlop, Malcolm G, Rudan, Igor, Campbell, Harry, Haley, Chris, Wright, Alan F, Wilson, James F, McKeigue, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778345/
https://ncbi.nlm.nih.gov/pubmed/23361219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.307
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