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Modification of the Pulmonary MyD88 Inflammatory Response Underlies the Role of the Yersinia pestis Pigmentation Locus in Primary Pneumonic Plague

Pneumonic plague, caused by Yersinia pestis, is a rapidly progressing bronchopneumonia involving focal bacterial growth, neutrophilic congestion, and alveolar necrosis. Within a short time after inhalation of Y. pestis, inflammatory cytokines are expressed via the Toll/interleukin-1 (IL-1) adaptor m...

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Udgivet i:Infect Immun
Main Authors: Olson, Rachel M., Dhariwala, Miqdad O., Mitchell, William J., Skyberg, Jerod A., Anderson, Deborah M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097263/
https://ncbi.nlm.nih.gov/pubmed/33257532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00595-20
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