Metformin Modulates T Cell Function and Alleviates Liver Injury Through Bioenergetic Regulation in Viral Hepatitis

Metformin is not only the first-line medication for the treatment of type 2 diabetes, but it is also effective as an anti-inflammatory, anti-oxidative and anti-tumor agent. However, the effect of metformin during viral hepatitis remains elusive. Using an adenovirus (Ad)-induced viral hepatitis mouse...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Xu, Lanman, Wang, Xiaofang, Chen, Yan, Soong, Lynn, Chen, Yongping, Cai, Jiyang, Liang, Yuejin, Sun, Jiaren
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097169/
https://ncbi.nlm.nih.gov/pubmed/33968030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.638575
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