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Type 1 interferon-induced IL-7 maintains CD8(+) T-cell responses and homeostasis by suppressing PD-1 expression in viral hepatitis
Type 1 interferon (IFN-I) promotes antigen-presenting cell maturation and was recently shown to induce hepatic IL-7 production during infection. Herein, we further explored the underlying mechanisms used by IFN-I to orchestrate antiviral immune responses in the liver. Acute viral hepatitis was induc...
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| Izdano u: | Cell Mol Immunol |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4654295/ https://ncbi.nlm.nih.gov/pubmed/25027969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2014.49 |
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