YWHAE-NUTM2 oncoprotein regulates proliferation and cyclin D1 via RAF/MAPK and Hippo pathways

Endometrial stromal sarcoma (ESS) is the second most common subtype of uterine mesenchymal cancer, after leiomyosarcoma, and oncogenic fusion proteins are found in many ESS. Our previous studies demonstrated transforming properties and diagnostic relevance of the fusion oncoprotein YWHAE–NUTM2 in hi...

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Bibliografiske detaljer
Udgivet i:Oncogenesis
Main Authors: Ou, Wen-Bin, Lundberg, Meijun Z., Zhu, Shuihao, Bahri, Nacef, Kyriazoglou, Anastasios, Xu, Liangliang, Chen, Ting, Mariño-Enriquez, Adrian, Fletcher, Jonathan A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097009/
https://ncbi.nlm.nih.gov/pubmed/33947829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-021-00327-w
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