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‘Targeting ectonucleotidases to treat inflammation and halt cancer development in the gut’
CD39 and CD73 control cell immunity by hydrolyzing proinflammatory ATP and ADP (CD39) into AMP, subsequently converted into anti-inflammatory adenosine (CD73). By regulating the balance between effector and regulatory cells, these ectonucleotidases promote immune homeostasis in acute and chronic inf...
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| Publicado no: | Biochem Pharmacol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8096647/ https://ncbi.nlm.nih.gov/pubmed/33460629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2021.114417 |
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