A cyclic peptide inhibitor of the SARS-CoV-2 main protease

This paper presents the design and study of a first-in-class cyclic peptide inhibitor against the SARS-CoV-2 main protease (M(pro)). The cyclic peptide inhibitor is designed to mimic the conformation of a substrate at a C-terminal autolytic cleavage site of M(pro). The cyclic peptide contains a [4-(...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Eur J Med Chem
Main Authors: Kreutzer, Adam G., Krumberger, Maj, Diessner, Elizabeth M., Parrocha, Chelsea Marie T., Morris, Michael A., Guaglianone, Gretchen, Butts, Carter T., Nowick, James S.
Format: Artigo
Sprog:Inglês
Udgivet: The Author(s). Published by Elsevier Masson SAS. 2021
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096527/
https://ncbi.nlm.nih.gov/pubmed/34023738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2021.113530
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker