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Robo recruitment of the Wave regulatory complex plays an essential and conserved role in midline repulsion

The Roundabout (Robo) guidance receptor family induces axon repulsion in response to its ligand Slit by inducing local cytoskeletal changes; however, the link to the cytoskeleton and the nature of these cytoskeletal changes are poorly understood. Here, we show that the heteropentameric Scar/Wave Reg...

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Publicat a:eLife
Autors principals: Chaudhari, Karina, Gorla, Madhavi, Chang, Chao, Kania, Artur, Bashaw, Greg J
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096436/
https://ncbi.nlm.nih.gov/pubmed/33843588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64474
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