Whole-genome sequencing analysis of semi-supercentenarians

Extreme longevity is the paradigm of healthy aging as individuals who reached the extreme decades of human life avoided or largely postponed all major age-related diseases. In this study, we sequenced at high coverage (90X) the whole genome of 81 semi-supercentenarians and supercentenarians [105+/11...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:eLife
المؤلفون الرئيسيون: Garagnani, Paolo, Marquis, Julien, Delledonne, Massimo, Pirazzini, Chiara, Marasco, Elena, Kwiatkowska, Katarzyna Malgorzata, Iannuzzi, Vincenzo, Bacalini, Maria Giulia, Valsesia, Armand, Carayol, Jerome, Raymond, Frederic, Ferrarini, Alberto, Xumerle, Luciano, Collino, Sebastiano, Mari, Daniela, Arosio, Beatrice, Casati, Martina, Ferri, Evelyn, Monti, Daniela, Nacmias, Benedetta, Sorbi, Sandro, Luiselli, Donata, Pettener, Davide, Castellani, Gastone, Sala, Claudia, Passarino, Giuseppe, De Rango, Francesco, D'Aquila, Patrizia, Bertamini, Luca, Martinelli, Nicola, Girelli, Domenico, Olivieri, Oliviero, Giuliani, Cristina, Descombes, Patrick, Franceschi, Claudio
التنسيق: Artigo
اللغة:Inglês
منشور في: eLife Sciences Publications, Ltd 2021
الموضوعات:
Genetics and Genomics
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096429/
https://ncbi.nlm.nih.gov/pubmed/33941312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57849
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