Whole-genome sequencing analysis of semi-supercentenarians

Extreme longevity is the paradigm of healthy aging as individuals who reached the extreme decades of human life avoided or largely postponed all major age-related diseases. In this study, we sequenced at high coverage (90X) the whole genome of 81 semi-supercentenarians and supercentenarians [105+/11...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Garagnani, Paolo, Marquis, Julien, Delledonne, Massimo, Pirazzini, Chiara, Marasco, Elena, Kwiatkowska, Katarzyna Malgorzata, Iannuzzi, Vincenzo, Bacalini, Maria Giulia, Valsesia, Armand, Carayol, Jerome, Raymond, Frederic, Ferrarini, Alberto, Xumerle, Luciano, Collino, Sebastiano, Mari, Daniela, Arosio, Beatrice, Casati, Martina, Ferri, Evelyn, Monti, Daniela, Nacmias, Benedetta, Sorbi, Sandro, Luiselli, Donata, Pettener, Davide, Castellani, Gastone, Sala, Claudia, Passarino, Giuseppe, De Rango, Francesco, D'Aquila, Patrizia, Bertamini, Luca, Martinelli, Nicola, Girelli, Domenico, Olivieri, Oliviero, Giuliani, Cristina, Descombes, Patrick, Franceschi, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096429/
https://ncbi.nlm.nih.gov/pubmed/33941312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57849
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